Alliance for Substance Abuse Progress

Medication-Assisted Treatment

Medication-assisted treatment (MAT) is an evidence-based treatment approach for opioid use disorder and addiction which combines medication, behavioral counseling and support to reduce cravings and prevent withdrawal symptoms and relapse. MAT is proven to be clinically effective in treating opioid addiction.

Administering these medications does not produce a high or simply substitute one addiction for another. These medications, in combination with therapy, allow the brain and body to heal and learn to replace unhealthy behaviors with healthy ones.

  • Methadone – Methadone prevents withdrawal symptoms and reduces cravings without producing a high. It is taken daily and can only be administered through a federally-licensed opioid treatment program.
  • Suboxone – A combination of buprenorphine and naloxone (Suboxone) is used to prevent withdrawal symptoms and reduce cravings without producing a high. It can be administered by certified physicians or federally-licensed opioid treatment programs.
  • Naltrexone – Naltrexone (Vivitrol) is a monthly injection used to treat opioid dependence. It blocks the effects of opioids, reduces cravings and helps prevent relapse. It can only be taken when the individual is 100% drug-free. Naltrexone is available as a pill taken daily or a monthly injection.

Additional details available at:

Last modified on Friday, 3 April 2020 10:51